ISRS 2026 Preliminary Scientific Program

 
  ISRS Educational Course   Oral Presentation
  Breakfast Seminar   Plenary Session
  Parallel Session   Keynote Lecture
08:30 10:00 ISRS Educational Course – 1
BASIC PRINCIPLES & GENERAL INDICATIONS OF RADIOSURGERY

Welcome and Introduction
Principles of Radiosurgery
Basic Radiosurgery Radiobiology
Quality Assurance in Radiosurgery
Radiosurgery for Brain Metastases
Spinal Radiosurgery
Q&A
Presentation of the Hands-on Cases & Organization
10:00 10:30 Coffee Break
10:30 12:00 ISRS Educational Course – 2
BRAIN, incl. Repeat SRS (parallel)
Intracranial Benign Lesions
Vascular Malformations
Functional SRS for Tremor and Facial Pain
Malignant Primary Tumors
Complications – Radiation Necrosis: Imaging and Management
Q&A
12:00 13:30 Lunch
13:30 16:30 Presentations & Hands-On with the Participation of the Leading SRS and SBRT Companies
16:30 17:00 Comfort Break
17:00 18:30 Opening Ceremony & Welcome Reception
10:30 12:00 ISRS Educational Course – 3
SBRT (parallel)
End to end automation with AI and workflow optimisation for same-day curative SBRT Principles of MRI-guided RT
Lung
Prostate
Pancreas & Liver
SABR/SBRT for Kidney and Adrenal; Conceptualisation to Implementation
Q&A
12:00 13:30 Lunch
13:30 16:30 Presentations & Hands-On with the Participation of the Leading SRS and SBRT Companies (parallel)
16:30 17:00 Comfort Break
17:00 18:30 Opening Ceremony & Welcome Reception
13:00 15:00 Leading Tumor Board Discussions on Non Surgical Treatment for Borderline
Resectable Lung Cancer – Drew Moghanaki

This session is suitable for people managing lung cancer patients and who work as part of a multi-disciplinary team.
The session will be focused in particular on the borderline resectable patient.
08:00 09:00 Extracranial Breastfast Seminar
Advances in SBRT
Moderators: Rupesh Kotecha, Piet Dirix
Paediatric / Adolescent / Young Adult SBRT – Erin Murphy
AI Platform for Targeted SBRT to Halve Toxicity – Paul Keall
Protons in SRS and SABR – Alexander Louie
09:00 09:20 Welcome to Country
Cecelia Gzell, Arjun Sahgal
09:20 10:10 Keynote Lecture 1
Moderator: Cecelia Gzell

Co-creating Care: The Power of the Patient Voice Lucinda Morris
Bedside to Headline: The Power of the Patient Voice- Rosanna Martinello
The Power of Putting Patients at the Centre of Radiosurgery – Drew Moghanaki
10:10 11:00 Plenary Session – Intracranial
Artificial Intelligence, Radiomics, Imaging Updates
Moderators: Thierry Gevaert, Mihir Shanker

Data Science in Radiotherapy – TBA
Innovation in AI Technologies for Diagnostic Radiology – Nalan Ertas
Use of AI in the Oncology Clinic – Ben Condon
11:00 11:30 Coffee Break & Exhibition
11:30 12:30 Oral Presentation – Intracranial
Quality Assurance and Dosimetry
Moderators: TBA, Paul Keall

11:30 – 11:50 ISRS Certification Service – Ian Paddick
11:50 – 12:10 Microbeam Radiation Therapy: therapeutic advantages and technological challenges – Marco Petasecca
12:10 -12:22 Multi-Institutional Film Dosimetry Audit in Multi-Focal SRS: Variability in Gamma Performance and Plan Quality Across Centers, Treatment Modalities, and Treatment Planning Systems – Evangelos Pappas
12:22 -12:34 Advanced Optimization Approaches For Enhancing Precision In Cone-Based Radiosurgical Treatment Planning Of Trigeminal Neuralgia – Raghavendra Holla
12:30 13:30 Parallel Session – Extracranial
Spine
Moderators: Arjun Sahgal, Matthew Foote

Clinical Applications of Spine SBRT – Daniel Tan
Spine SBRT / VCF – Amol J. Ghia
Primary Spine Tumours – Simon Lo
13:30 14:45 Lunch & Sponsored Lunch Symposium
14:45 15:45 Plenary Session – Extracranial
Emerging SBRT Indications
Moderators: Simon Lo, Shankar Siva
Celiac Plexus SRS – Michael Chuong
Cardiac SBRT – Joost Verhoeff
Beyond Conventional Fractionation: The Rising Role of SBRT in Head and Neck Cancer – Sweet Ping Ng
15:45 16:45 Oral Presentation – Intracranial
Young Investigator Session
Moderators: Kimberley Budgen, Cecelia Gzell
Induction Stereotactic Radiosurgery Remodels the Glioblastoma Immune Microenvironment via Calreticulin-Mediated Immunogenic Cell Death: A Translational Proof-of-Concept Study – Yun Guan
Effect of Non-Consecutive Treatment During Hypo-Fractionated Stereotactic Radiosurgery (HF-SRS) for Brain Metastases – Michael Schulder
NADPH Oxidase 3 Inhibition Preserves Hearing in Mice After Stereotactic Radiosurgery – Marc Levivier
Evaluation of a Commercial Synthetic-CT for SRS Brain Treatments – Marc Levivier
16:45 17:15 Coffee Break & Exhibition
17:15 18:15 Oral Presentation – Intracranial
Brain Metastases
Moderator: Shoji Yomo
Trial in Progress: EXCLAIM: Exploring Combined Local and Systemic Approaches in Brain Metastasis: A Randomized Phase II Study Evaluating Response to Systemic Therapy and Integration of Radiosurgery for Brain Metastases – Thomas Beckham
Baseline and Time-Dependent Predictors of Cognitive Decline for Brain Metastasis Patients Treated with Radiotherapy – A Secondary Analysis of the ATHENA Trial – Fatemeh Fekrmandi
Tumor Dynamics, Dosimetric Impact, and Predictors of Geometric Changes During Multi-Day Adaptive Stereotactic Radiosurgery for Multiple Brain Metastases – Arjun Sahgal
Propensity Score–Matched Subanalysis of Stereotactic Radiosurgery for Metastatic Brain Tumors Using the Leksell Gamma Knife Icon Mask System: Impact of Metastasis Number and Tumor Volume Beyond the JLGK0901 Criteria – Yuta Oi
Preliminary Clinical Study Using Magnetic Resonance Fingerprinting and Intravoxel Incoherent Motion Imaging to Differentiate Radiation Necrosis from Tumor Recurrence Following Stereotactic Radiosurgery – Samuel Chao
19:00   President’s Dinner
(invitation only)
11:00 11:30 Coffee Break & Exhibition
11:30 12:30 Oral Presentation – Intracranial
Pediatrics
Moderators: Erin Murphy, Andrew Pullar

Patterns of Care and Outcomes of Stereotactic Radiosurgery for Radiation-Induced Meningiomas: A Single-Institution Cohort Analysis – Randy Jensen
Gamma Knife for Residual Vein of Galen Malformations in Children: The Great Ormond Street and Queen Square Experience – Ian Paddick
Stereotactic Radiosurgery, Brachytherapy or Enucleation for Uveal Melanoma: Comparison of Outcomes in Comparable Groups – Andrey Yarovoy
Hypofractionated Stereotactic Radiotherapy for Uveal Melanoma – Isa Bossi Zanetti
Risk-Adapted Stereotactic Radiation for NF2-Related Schwannomatosis: Lesion-Based Prescription Patterns for Meningiomas and Cranial Nerve Schwannomas – Sergio Moreno-Jimenez
12:30 13:30 Parallel Session – Intracranial
QoL / Survivorship / Rehabilitation
Moderators: Margaret Hjorth, Mihir Shanker

Changes in Pediatric Brain Tumor Radiation Over Time – Erin Murphy
From Planning to Practice: Nursing Perspectives in Establishing a Gamma Knife Department – Jade Fitzgerald
Innovating Nursing Support in Specialised Care: A Scalable Remote Model applied to our Gamma Knife service – Margaret Hjorth
13:30 14:45 Lunch & Sponsored Lunch Symposium
15:45 16:45 Oral Presentation – Intracranial
Radiobiology
Moderator: Ian Paddick,Michael Rodriguez

The Role of Biologically Effective Dose in Clinical Improvement and Hyperresponse After Gamma Knife Radiosurgery for Essential Tremor – Constantin Tuleasca
Variation of the Biological Effective Dose (BED) Delivered Depending on Treatment Device – Ian Paddick
What Does BED Add?: A Preliminary Investigation Using Information Criteria Metrics – David Schlesinger
Diagnostic Performance Of Treatment Response Assessment Maps (TRAM) In Detecting Tumor Recurrence Versus Adverse Radiation Effect After Brain Radiation – Zachary Seymour
Retrospective Study for Lens Dose in Gamma Knife Treatment – Ana Luisa Luis
16:45 17:15 Coffee Break & Exhibition
17:15 18:15 Oral Presentation – Intracranial
Vestibular Schwannomas
Moderator: Samuel Chao

Tumour, Treatment, and Transformation: A Prospective Study of Quality of Life Trajectories in Vestibular Schwannoma – Manjul Tripathi
Subtotal Resection with Adjuvant Radiosurgery Versus Gross Total Resection for Large Vestibular Schwannomas: Comparative Outcomes in Cranial Nerve Preservation and Tumor Control – Isaac Yang
Volumetric Outcomes of Hypofractionated Gamma Knife Stereotactic Radiosurgery for Koos Grade III and IV Vestibular Schwannomas: A Comparative Analysis – Michael Schulder
Early Volumetric Reduction After Gamma Knife Radiosurgery in Newly Diagnosed Cystic Vestibular Schwannoma of Koos Grade III–IV – Michael Schulder
Clinical and Radiological Outcomes of Vestibular Schwannoma After Stereotactic Radiosurgery According to Tumor Size – Ji Woo An
19:00   President’s Dinner
(invitation only)
11:00 11:30 Coffee Break & Exhibition
11:30 12:30 Parallel Session – Extracranial Thoracic
Moderators: Shankar Siva, Simon Lo
Lung – operable and MRgRT – Drew Moghanaki
Lung SBRT in Context of ILD – Alex Louie
Lung SBRT – Central / Ultracentral – Louis Lao
12:30 13:30 Parallel Session – Intracranial
Meningiomas
Moderators: Mark Pinkham, Laura Fariselli
Imaging Updates in Meningioma Management – Raj Singh
Emerging Theranostics – Geoffrey Schembri
Molecular Genetics Updates in Meningiomas – Michael Rodriguez
13:30 14:45 Lunch & Sponsored Lunch Symposia
15:45 16:45 Oral Presentation – Intracranial Artificial Intelligence in Radiosurgery
Moderator: Mihir Shanker
An Automated Pipeline for Brain Tumour Segmentation on MRI Images for Gamma Knife Radiosurgery – Prabhakar Ramachandran
Evaluating Clinical Acceptance of Artificial Intelligence Driven Auto-Segmentation for Brain Metastases – Helen Truong
A Web-Based Software Platform for Vestibular Schwannoma Auto-Segmentation and Treatment Follow-Up – Gregory Szalkowski
Patient and MRI Specific Distortion Correction in Enhancing Dosimetric Accuracy with Stereotactic Radiosurgery – Zachary Seymour
16:45 17:15 Coffee Break & Exhibition
17:15 18:15 Parallel Session – Extracranial
Liver Metastases
Moderators: TBA, Louis Lao
ISRS Guideline: SBRT for Liver Metastases – Chi Leung Chiang
Real World Outcomes of SBRT for Liver Metastases – a 10-year, Single-Institutional Analysis – Yoo Young (Dominique) Lee
19:00 President’s Dinner
(invitation only)
08:00 09:00 Intracranial Breakfast Seminar
Moderators: Sarah Olson, Samuel Chao
From Elite Institutions to Emerging Markets: Making State-of-the-Art SRS Accessible to All – Sebastian Adamczyk
09:00 09:30 Lars Leksell Lecture
09:30 10:30 Plenary Session – Intracranial
Physician Care: Burnout and Building Resilience
Moderators: Matthew Foote, Neda Haghighi
MDOK – Sarah Michael
Resilience – Geoff Toogood
Physician Care and Wellness – Yoo Young Lee
10:30 11:00 Coffee Break & Exhibition
11:00 11:30 Fabrikant Award & Lecture
11:30 12:30 Plenary Session – Intracranial
Patient Advocacy and Social Media
Moderators: Margaret Hjorth, Matthew Foote
Cancer-aid Journey – Raghav Murali-Ganesh
Navigating Social Media for Doctors – Drew Moghanaki
Stereotactic Social Media: Amplifying patient impact and medical outreach – Isaac Yang
12:30 13:45 Lunch & Sponsored Lunch Symposium
13:45 15:00 Plenary Session – Intracranial
Emerging Indications / Functional / Other Focal Therapies
Moderator: Sarah Olson, Antonio De Salles

Focussed ultrasound – Ben Jonker
LITT – Veronica Chiang
Radiosurgery for Pain, Epilepsy, Tremor, Psychiatry – Alessandra Gorgulho
Emerging Role of FLASH RT in Pediatric Oncology – Robyn Gartrell
15:00 17:35 SIGA Symposium
15:00 – 15:05 Acknowledgement of Country / Welcome Address –Neda Haghighi
15:05 – 15:25 Lecture 1: The history and evolution of radiosurgery in Australia – Robert Smee
15:30 – 15:50 Lecture 2: Medical management of melanoma brain metastases in Australia including current and upcoming trials – Annie Wong
15:50 – 16:10 Lecture 3: Challenges in management of Chordoma in Australia –Matthew Foote & Jun Kim
16:15 – 16:45 Debate: The Impact of AI on SRS and Neurosurgery –Daniel Trifiletti & Veronica Chiang & Dheerendra Prasad
16:50 – 17:00 Closing Remarks Neda Haghighi
17:35 18:20  ISRS General Assembly & Business Meeting
12:30 13:45 Lunch & Sponsored Lunch Symposium
15:00 16:00 Parallel Session – Intracranial
SRS in Gliomas and Primary Brain Tumours

Moderator: Rupesh Kotecha, Cecelia Gzell
Systemic Therapy and Clinical Trials for Primary Brain Tumours – Hao Wen
SRS Primary Tumours – Sunil W. Dutta
Neurocognitive Sequelae of SRS Treatment for Gliomas – Glenn Stevens
12:30 13:45 Lunch & Sponsored Lunch Symposium
15:00 16:00 Parallel Session – Extracranial
Abdo
Moderators: Jarad Martin
SBRT for HCC: The Future is Bright – David Pryor
Pancreas SBRT – Yoo Young (Dominique) Lee
Combination IO and SBRT/Liver – Chi Leung CHIANG
16:00 18:30 Brain Cancer Australia Consortium Session
09:00 10:00

Keynote Lecture

Moderator: Matthew Foote
Evolution of Spine RadiotherapyArjun Sahgal

10:00 11:00 Plenary Session – Extracranial
RCC, Oligomets
Moderators: Wee Loon Ong, Alex Louie
Non-spine bone mets – Quynh Nguyen
Prostate Oligomets – Stephane Supiot
RCC Oligomets – Simon Lo
11:00 11:30 Coffee Break & Exhibition
11:30 12:30 Oral Presentation – Intracranial Benign
Moderator: Dheerendra Prasad, Cecelia Gzell
The Impact of Biologically Effective Dose on Volumetric Decrease After Upfront Stereotactic Radiosurgery for Intracranial Meningiomas – Constantin Tuleasca
Re-Irradiation Outcomes Following Salvage Conventionally Fractionated Gamma Knife Stereotactic Radiotherapy (SFGK) To Recurrent Primary Non-Glial Brain Tumours – Cristian Udovicich
Long Term Follow Up for Meningioma Patients After SRS: Cognitive and Quality of Life (QOL) Data – Anna Bangiri
Efficacy and Safety of Stereotactic Radiosurgery as a Primary Treatment for Central Neurocytoma: From Single-Fraction to Staged Hypofractionation Strategies – Yun Guan
Linac Based Frameless Single Fraction Versus Fractionated Radiosurgery for Vestibular Schwannomas – A Single Institution Experience from a Tertiary Cancer Centre Assessing Hearing Preservation Rates, Local Control and Toxicity – Sanjay Hunugundmath
12:30 13:30 Oral Presentation – Intracranial Pituitary/Parasellar
Moderator: Sarah Olson, Neda Haghighi
Multisession Radiosurgery for Non-Functioning Pituitary Adenoma: An Exploratory Prospective Study – Laura Fariselli
GA-68 Dotatate PET/CT Enhances Target Delineation in Dural Stereotactic Radiotherapy – He Wang
The Role of Stereotactic Radiosurgery and Hypofractionated Radiotherapy in the Management of Pituitary Adenomas with Cavernous Sinus Invasion: A Single-Center Experience Since 2005 – Andrey Golanov
A Comparative Carbon Footprint Analysis Of Gamma Knife Radiosurgery And Surgical Resection In A Case Of Intracranial Meningioma – Selçuk Peker
Dosimetric Comparison of HyperArc Versus Coplanar VMAT in Fractionated Stereotactic Radiotherapy for Pituitary Adenomas – Sin Ting Chan
13:30 14:45 Lunch & Sponsored Lunch Symposia
14:45 15:45 Parallel Session – Intracranial
Vestibular Schwannomas
Moderators: Marc Levivier, Selçuk Peker
Complex management of NF2 – Katrina Morris
Beyond Tumour Control: Vestibular Dysfunction After SRS for Vestibular Schwannoma – Gretta Palmer
SRS for Vestibular Schwannomas – Isaac Yang
15:45 16:15 Coffee Break & Exhibition
16:15 17:15 Oral Presentation – Extracranial
Thoracic
Moderators: Louis Lao, Alex Louie
Safety And Efficacy Of Stereotactic Body Radiotherapy For Central And Ultracentral Earlystage Lung Tumors: A Canadian Provincial Cancer Center Experience – Vibhay Pareek
Expanding the Therapeutic Window in Lung SBRT: The Role of Respiratory Motion Management – Thierry Gevaert
Reduced Planning Target Volume Margins in Central Lung Stereotactic Body Radiation Therapy with CyberKnife Fiducial Tracking – Ashlesha Gill
Markerless Breath-Hold SBRT for Lung Lesions Using Stereoscopic X-Rays and Anatomical Correlation Objects: A Prospective Feasibility Study – Thierry Gevaert
Spare: Segment-Targeted Precision Ablative Radiotherapy to Control Radiation Pneumonitis by Limiting Low-Dose Exposure to Involved Pulmonary Segments – Shinya Neri
17:15 17:35 ISRS Awards & Closing Session
19:00 22:00 Congress Farewell Dinner
11:00 11:30 Coffee Break & Exhibition
11:30 12:30 Oral Presentation – Intracranial
Vascular
Moderator: Matthew Foote, Mark Dexter
Stereotactic Radiosurgery for Spinal Cord Arteriovenous Malformations – Scott Soltys
Gamma Knife Radiosurgery of Arteriovenous Malformations: Summary of Experience in 15 Years at Cho Ray Hospital – Nguyen Binh
Navigating Management of High-Grade AVMs: Results and Risk Stratification in Hypofractionated Gamma Knife Radiosurgery – Manjul Tripathi
Seizure Outcomes After Linac Radiosurgery for Unruptured Brain Arteriovenous Malformations: A 7-Year Retrospective Cohort Study – Jose Omar Santellan
Beyond the Bottleneck: A Modern, Frameless Workflow for Scalable and Advanced Cerebral AVM Radiosurgery – David Stewart
12:30 13:30 Oral Presentation – Extracranial
GU
Moderators: Stephane Supiot, Michael Huo
Stereotactic Body Radiotherapy With 42.7 Gy In 7 Fraction For Localized Prostate Cancer: Real World Clinical Experience – Christina Schröder
Prostate Stereotactic Body Radiotherapy with a MRI Defined Focal Simultaneous Integrated Boost to the Dominant Intraprostatic Nodule: Toxicity Profile and Clinical Outcomes – Isa Bossi Zanetti
FROGG Consensus Clinical Practice Guideline on Stereotactic Ablative Body Radiotherapy for Prostate Cancer – Therese Kang
A Radiomic Machine Learning Model To Predict Prostate Cancer Response To Cyberknife Treatment – Isa Bossi Zanetti
First Argentinian Experience With Stereotactic Body Radiotherapy (SBRT) For Oligometastatic Gynecological Cancer – Lucas Caussa
13:30 14:45 Lunch & Sponsored Lunch Symposium
14:45 15:45 Parallel Session – Extracranial
GU
Moderators: David Pryor
Prostate SBRT – Jarad Martin
Kidney / Adrenal SBRT – Simon Lo
Upper Tract Urothelial – Michael Huo
15:45 16:15 Coffee Break & Exhibition
16:15 17:15 Oral Presentation – General SBRT
Moderators: Cristian Udovicich, Wee Loon Ong
Sabrvical: A Randomised Open-Label Phase II Trial to Assess the Safety and Efficacy of Stereotactic Ablative Body Radiotherapy as a Boost After Chemoradiotherapy for Stage IB3-IIIC1 Cervical Carcinoma – Christian Haydee Flores-Balcázar
A Systemic Review Of Outcomes Of Non-Spine Bone Metastases Treated With Single Versus Multi-Session Stereotactic Body Radiotherapy – Joseph Cheng
Lattice Radiotherapy for Bulky and Recurrent Head and Neck Tumors: A Institutional Experience – Lucas Caussa
SBRT Fractionation Drives Anti-Tumor Immunity in a Preclinical NSCLC Model – Léa Bouchard
Improving SBRT with RadioPDT for Bone Metastases – Deepak Dinakaran
17:15 17:35 ISRS Awards & Closing Session
19:00 22:00 Congress Farewell Dinner
11:00 11:30 Coffee Break & Exhibition
11:30 12:30 Oral Presentation – Extracranial
Spine
Moderators: Christopher Jackson, Shankar Siva
Predictors of Vertebral Compression Fracture Following Stereotactic Body Radiation Therapy in SINS Potentially Unstable Spinal Metastases – Laura Burgess
Outcomes and Toxicities of Spine Stereotactic Body Radiotherapy (SBRT) in Patients Treated with Immunotherapy – Matthew Susko
Impact of Contouring Guideline Adherence on Patterns of Failure in Sacral SBRT – Daniel Moore Palhares
Dose-Escalated Single Fraction Spine Stereotactic Radiosurgery for Chordoma of the Mobile Spine or Sacrum: Long-Term Results – Amol Ghia
Rapid Automatic High Quality Stereotactic Spinal Radiosurgery Planning by Adapting Library Plan – Xin Wang
12:30 13:30 Oral Presentation – Extracranial
Abdo
Moderators: Angela Yates, Deepak Dinakaran
Progressive Margin Reduction in Pancreas SBRT on MR-Linac with Target Intrafraction Tracking and Gating Using Comprehensive Motion Management (CMM) – Michele Rigo
Institutional Experience With SBRT Reirradiation For Locally Recurrent Rectal Cancer – Lucas Caussa
Interfraction Volumetric Changes of Patients Treated with Liver Stereotactic Body Radiation Therapy Using MRI-Guided Adaptive Planning – Einsley Janowski
4D Robust Optimization for Liver SBRT in CyberKnife – Ronnie Leung
Daily Adaptation of Abdominal SBRT Plans Using C-Arm Linac High Performance CBCT – Eun Young Han
13:30 14:45 Lunch & Sponsored Lunch Symposium
14:45 15:45 Parallel Session – Intracranial
Brain Metastases: SRS and Systemic Therapy
Moderators: Daniel Trifiletti, Najmun Nahar
Update on ABC-X Trial – Mark Pinkham
Update on Trials in EGFR Mutant Lung Cancer – Yu Yang Soon
Biology / Pathology – TBA
15:45 16:15 Coffee Break & Exhibition
16:15 17:15 Oral Presentation
Functional & Best of the Rest
Moderators: Ben Jonker
Long Term Results On A Large Cohort Of Patients Treated By Cyberknife Radiosurgery For Trigeminal Neuralgia – Isa Bossi Zanetti
Comparative Analysis of Single-Session Radiosurgery for Trigeminal Neuralgia: Gamma Knife Versus CyberKnife Outcomes in a Retrospective Cohort Study – Andrey Golanov
Novel Conformity Index for Optimization of Treatment Plans – Hyun-Tai Chung
Integral Dose as a Determinant of Sustained Pain Relief After Gamma Knife Radiosurgery as Primary Treatment for Typical Trigeminal Neuralgia – Adesh Shrivastava
17:15 17:35 ISRS Awards & Closing Session
19:00 22:00 Congress Farewell Dinner